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  1. Where is PDT used?

  2. How is PDT given?

  3. What should be avoided?

  4. How often should I follow up?

  5. What are the side effects?

  6. How do I get more information?


 

Where is PDT used?

 

There has been increasing use of photodynamic therapy (PDT) to treat neovascular AMD since FDA approval in 2000.  PDT has been shown to be effective in slowing the visual deterioration associated with some types of neovascular AMD.  In addition, this treatment is well tolerated without significant systemic adverse events. PDT relies on the tissue presence of a photosensitizing agent or dye that is subsequently activated by specific wavelength of light.  The only such agent currently approved is verteporfin (Visudyne).

 

How is PDT given?

 

Following the infusion of the dye, it accumulates preferentially in areas of choroidal neovascularization (CNV), the abnormal tissue causing visual loss in neovascular AMD.  Upon interaction with the light, the dye is transformed into an activated state resulting in damage and sclerosis of the CNV. The dye is first infused intravenously for 10 minutes.  Fifteen minutes after the start of the infusion, a laser light is delivered over the affected area for 83 seconds.

 

What should be avoided?

 

It is important for patients to avoid direct sunlight or bright light for 5 days after treatment to avoid photosensitivity reactions.  They should stay indoors during this time and limit skin exposure with the use of long protective clothing.  Sunscreen cannot be used as a substitute since it will not prevent damage to the skin with exposure.

 

How often should I follow up?

 

For at least the first two years following PDT, follow up visits are needed to determine if additional treatment needs to be done.

 

What are the side effects?

 

Side effects of the treatment include:

  1. mild and temporary visual disturbances

  2. back pain

  3. photosensitivity

  4. injection site reaction

  5. severe allergic reaction

 

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How do I get more information?

Please call your local eye care professional for more information. There are several ways of reaching the ophthalmologists of the EYE REPUBLIC Ophthalmology Clinic:

  1. Visit the EYE REPUBLIC Ophthalmology Clinic website at EyeRepublic.com.ph.

  2. Visit the Ophthalmic Consultants Philippines Co. website at OCP.com.ph.

  3. Email help@EyeRepublic.com.ph for general inquiries. After writing down your comments, suggestions, problems and/or questions, kindly tell us how to get in touch with you by providing your name, email, home/office numbers, and mobile phone.

  4. Place a blog comment at the EYE REPUBLIC Blog.

EYE REPUBLIC Ophthalmology Clinic

Manila

3/F Don Santiago Building (DSB) Units 309-310

1344 Taft Avenue, Ermita

Manila, 1000 Philippines

Direct and Fax: +63 (2) 536-2398

Trunk line: +63 (2) 523-8271 to 79 local 30

Cellular line: +63 (917) 899-2020

Map and directions

EYE REPUBLIC Ophthalmology Clinic

Asian Hospital and Medical Center

5/F Medical Office Building (MOB) Suite 509

2205 Civic Drive, Filinvest, Alabang

Muntinlupa City, 1781 Philippines

Direct: +63 (2) 771-9253

Direct and Fax: +63 (2) 771-9254

Cellular line: +63 (917) 795-2020

Map and Directions

EYE REPUBLIC Ophthalmology Clinic

Medical City

6/F Medical Arts Tower (MATI) Suite 602

MERALCO Compound, Ortigas Ave.

Pasig City, 1604 Philippines

Direct and Fax: +63 (2) 632-7846

Cellular line: +63 (917) 537-2020

Map and Directions

EYE REPUBLIC Ophthalmology Clinic

St. Luke's Medical Center

6/F Cathedral Heights Building Complex (CHBC) North Tower Suite 614

279 E. Rodriguez Sr. Boulevard

Quezon City, 1102 Philippines

Direct and Fax: +63 (2) 407-3883

Cellular line: +63 (917) 855-2020

Map and directions

CLINIC HOURS

Monday to Saturday 9:00 AM to 6:00 PM

All clinics are closed on Sundays and Holidays

 
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PHOTODYNAMIC THERAPY information compiled by Dr. Michael Santos and initially uploaded on August 7, 2005.

 

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